In-vivo Transcutaneous Electrical Stimulation with Validation of Simulation Model

Matlab was used to simulate the channels and ion currents. The channels could be defined as circuits, which are then further abstracted through equations. Matlab was the best tool for this type of analysis, but changing parameters proved to be a challenge.

The next level of analysis required circuit simulations for the muscle that were too complicated for Matlab to work on its own. Simulink was better suited for analyzing changes in the circuit signals at specific points. This allows us to observe how the signals changed as they passed through the layers of skin/muscle.

Finally, using COMSOL, we made a 3D model of the system using contact pads. We considered factors that may contribute to changes in the signal reaching the muscles, such as skin conductance or the presence of bones beneath the target muscle.